Author/Authors :
Amaral، نويسنده , , Patrيcia A. and Gouault، نويسنده , , Nicolas and Roch، نويسنده , , Myriam Le and Eifler-Lima، نويسنده , , Vera L. and David، نويسنده , , Michèle، نويسنده ,
Abstract :
Kavalactone derivatives were synthesized using a Heck reaction of the 4-methoxy-6-vinyl-5,6-dihydropyran-2-one with aryl iodides. The Suzuki–Miyaura reaction of an aryl boronic acid and (Z)-4-methoxy-6-(2-iodovinyl)-5,6-dihydropyran-2-one has also been successfully used to produce both Z and E isomers of lactones.
Keywords :
Kavalactones , Suzuki–Miyaura reaction , Yangonin , Heck reaction