Title of article
The first stereoselective and the total synthesis of Leiocarpin C and total synthesis of (+)-Goniodiol
Author/Authors
Yadav، نويسنده , , J.S. and Premalatha، نويسنده , , K. and Harshavardhan، نويسنده , , S.J. and Subba Reddy، نويسنده , , B.V.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
6765
To page
6767
Abstract
The synthesis of the styryl lactone Leiocarpin C has been achieved in a highly stereoselective manner using Jacobsen’s kinetic resolution, Sharpless asymmetric epoxidation and Sharpless asymmetric dihydroxylation as key steps. This is the first total synthesis of Leiocarpin C, and thus establishes for the first time the absolute stereochemistry of this natural product.
Keywords
styryl lactones , sharpless asymmetric dihydroxylation , Jacobsen’s kinetic resolution , Sharpless asymmetric epoxidation
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861655
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