Title of article :
Synthesis of novel annulated uracils via domino Knoevenagel-hetero-Diels–Alder reaction in aqueous media
Author/Authors :
Khoshkholgh، نويسنده , , Malihe Javan and Balalaie، نويسنده , , Saeed and Bijanzadeh، نويسنده , , Hamid Reza and Rominger، نويسنده , , Frank B. Gross، نويسنده , , Jürgen H.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
An efficient synthesis of tetracyclic uracil derivatives (polycyclic pyrans) is achieved via domino Knoevenagel-hetero-Diels–Alder reactions of O-propargylated salicylaldehyde derivatives with 1,3-dimethylbarbituric acid in water as solvent in the presence of CuI. The products are formed in good yields.
Keywords :
Cuprous iodide , Unactivated alkynes , Tetracyclic uracil , aqueous media , Domino intramolecular Knoevenagel-hetero-Diels–Alder
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
