Title of article
First synthesis of (+)-myxothiazol A
Author/Authors
Iwaki، نويسنده , , Yuki and Kaneko، نويسنده , , Masahiro and Akita، نويسنده , , Hiroyuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
7024
To page
7026
Abstract
First convergent synthesis of (+)-myxothiazol A (1) was achieved based on modified (one-pot) Julia olefination between (3,5R)-dimethoxy-(4R)-methyl 6-oxo-(2E)-hexenamide (2), corresponding to left-side of the final molecule, and E-4-2′-(1S,6-dimethylheptadiene)-(2,4′-bis-thiazole)-4-methybenzothiazole sulfone (4) corresponding to right-side.
Keywords
total synthesis , asymmetric synthesis , Modified Julia olefination , Myxothiazol A , antibiotic
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1861829
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