Author/Authors :
Shen، نويسنده , , Wang and Kohn، نويسنده , , Todd and Fu، نويسنده , , Zice and Jiao، نويسنده , , XianYun and Lai، نويسنده , , Sujen and Schmitt، نويسنده , , Michael، نويسنده ,
Abstract :
A mild and efficient method for the preparation of substituted benzimidazoles from 1,1-dibromoethenes and o-diaminobenzenes is described. The reaction employs DABCO as the base and NMP as the solvent. A variety of substitutions on both 2-aryl-1,1-dibromoethenes and o-diaminobenzenes are tolerated. This new procedure is carried out under mildly basic conditions, which may provide a complementary route to the existing preparations of benzimidazoles.
