tert-Butyl isocyanide revisited as a convertible reagent in the Groebke–Blackburn reaction

tert-Butyl isocyanide can serve as the convertible reagent in Groebke–Blackburn multi-component reactions. The effective removal of the tert-butyl group from the resulting imidazo[1,2-a]azines and -azoles is achieved on a gram scale in two steps without chromatographic purification.