Title of article
First asymmetric total synthesis of novel and cytotoxic 2′-R-hydroxylanneaquinol
Author/Authors
Suresh، نويسنده , , V. J. Rajesh، نويسنده , , K. and Jon Paul Selvam، نويسنده , , J. and Venkateswarlu، نويسنده , , Y.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2008
Pages
3
From page
7358
To page
7360
Abstract
A novel cytotoxic alkylated hydroquinone 2′-R-hydroxylanneaquinol (1), isolated from the organic extract of the plant Lannea welwitschii, has been synthesized for the first time using commercially available 4-methoxyphenol. The key step of this process involves the kinetic resolution of epoxide 6 using Jacobsen’s reaction conditions.
Keywords
2?-R-Hydroxylanneaquinol , Jacobsen’s resolution , asymmetric synthesis
Journal title
Tetrahedron Letters
Serial Year
2008
Journal title
Tetrahedron Letters
Record number
1862054
Link To Document