Title of article :
Efficient syntheses of enantioenriched (R)-pipecolic acid and (R)-proline via electrophilic organocatalytic amination
Author/Authors :
Kalch، نويسنده , , Delphine and Rycke، نويسنده , , Nicolas De and Moreau، نويسنده , , Xavier and Greck، نويسنده , , Christine، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
Five-step syntheses of (R)-pipecolic acid and (R)-proline are described, respectively, from cyclohexene and cyclopentene. The key step involves the organocatalytic α-amination of functionalized aldehydes.
Keywords :
Cyclic aminoacid , amination , Enantioselectivity , organocatalysis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
