Efficient solid-phase synthesis of perfluoroalkylated dimerizable cationic detergents for gene delivery
Author/Authors :
Guilloteau، نويسنده , , Nicolas and Gourriérec، نويسنده , , Loïc Le and Fabio، نويسنده , , Karine and Giorgio، نويسنده , , Christophe Di and Greiner، نويسنده , , Jacques and Vierling، نويسنده , , Pierre، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Pages :
2
From page :
562
To page :
563
Abstract :
A new straightforward solid-phase synthesis of perfluoroalkylated dimerizable detergents used as gene delivery systems is presented. This route using Fmoc-Cys(SASRIN™_®)-OH resin as solid support affords the target products in almost quantitative yields and high purity.
