Title of article :
Aza-annulation of β-enaminolactones: application to the synthesis of enantiopure difunctionalized bicyclic lactams
Author/Authors :
Alladoum، نويسنده , , Jeanne and Toum، نويسنده , , Valérie and Hebbe، نويسنده , , Séverine and Kadouri-Puchot، نويسنده , , Catherine and Dechoux، نويسنده , , Luc، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Pages :
3
From page :
617
To page :
619
Abstract :
Diastereoselective aza-annulation of seven-membered β-enaminolactones 2 gives access to bicyclic heterocyles 5. Fragmentation of molecule 5a with lithium methoxide affords cis or trans bicyclic lactams 8 with excellent stereoselectivities.
Keywords :
aza-annulation , bicyclic lactams , ?-enaminoesters , intramolecular Michael addition
Journal title :
Tetrahedron Letters
Serial Year :
2009
Journal title :
Tetrahedron Letters
Record number :
1862527
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1862527
بازگشت