Author/Authors :
Rai، نويسنده , , Ganesha and Thomas، نويسنده , , Craig J. and Leister، نويسنده , , William F. Maloney، نويسنده , , David J.، نويسنده ,
Abstract :
The synthesis of several 1,2,5-oxadiazole-2-oxide (Furoxan) analogues is described herein. These compounds were prepared in an effort to probe the SAR around the phenyl substituent and oxadiazole core for our studies toward thioredoxin-glutathione reductase (TGR) inhibition and antischistosomal activity.