Title of article
A novel synthesis of N1-(substituted)-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-diones
Author/Authors
Turbiak، نويسنده , , Anjanette J. and Showalter، نويسنده , , H.D. Hollis Showalter، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
2
From page
1996
To page
1997
Abstract
A new synthesis of N1-(substituted)-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-diones, which are analogues of the natural product toxoflavin, is reported. Condensation of preformed alkyl or aryl hydrazones with 6-chloro-3-methyl-5-nitrouracil efficiently provides pyrimidotriazinediones in a three-step process that broadens the scope of R1 substituents.
Keywords
4-e]-1 , 4-triazine-5 , 7(1H , 6H)-diones , Hydrazones , Toxoflavin , Zinc , cyclizations , 2
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1863347
Link To Document