Title of article
Magnesium/methanol: an effective reducing agent for chemoselective reduction of pyrimidine-2(1H)-ones
Author/Authors
Singh، نويسنده , , Kamaljit S Singh، نويسنده , , Kawaljit، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
2219
To page
2221
Abstract
Magnesium in methanol is an effective reagent for the chemoselective reduction of pyrimidine-2(1H)-ones. Other reducible functionalities such as ester and alkene of enamine ester and uriedo carbonyl remain unaffected. This constitutes the first example of the formation of Biginelli 3,4-dihydropyrimidin-2(1H)ones through the reduction of pyrimidine-2(1H)-ones.
Keywords
Pyrimidine-2(1H)-ones , Sodium metal reduction , Reduction , Biginelli dihydropyrimidinones , Dissolved metal reduction
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1863516
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