Author/Authors :
Mino، نويسنده , , Takashi and Naruse، نويسنده , , Yoshiaki and Kobayashi، نويسنده , , Shohei and Oishi، نويسنده , , Shunsuke and Sakamoto، نويسنده , , Masami and Fujita، نويسنده , , Tsutomu، نويسنده ,
Abstract :
A new atropisomeric dihydrobenzofuran-based bisphosphine ligand 1 was easily prepared from 1,4-dibromo-2-fluorobenzene. This racemic bisphosphine (±)-1 was used as a ligand for the palladium-catalyzed Suzuki–Miyaura reaction of aryl chloride with arylboronic acids and Hartwig–Buchwald amination of aryl bromides with aniline derivatives. The optical resolution of (±)-1 was also carried out by HPLC with a chiral stationary phase column.
