One-step assembly of novel carbamoyl substituted 6-oxo-4,5,6,11-tetrahydropyrrolo[1,2-b][2,5]benzodiazocine

In this work we have synthesized novel pharmaceutically relevant pyrrolo[1,2-b][2,5]benzodiazocines based entirely on the use of MCR between heterocyclic aldehyde-acid, amines, and isonitriles. The developed synthetic strategy provides an efficient one-step route to rare heterocyclic scaffold of paramount interest.