Author/Authors :
Lee، نويسنده , , Chai-Ho and Jin، نويسنده , , Guo Fan and Joung، نويسنده , , Jung Gun and Lee، نويسنده , , Jong-Dae and Ban، نويسنده , , Hyun Seung and Nakamura، نويسنده , , Hiroyuki and Cho، نويسنده , , Jung-Keun and Kang، نويسنده , , Sang Ook، نويسنده ,
Abstract :
o-Carboranyl aminoalcohols were synthesized using a standard Mannich reaction, and were tested for their anticancer properties using an in vitro test for CT26 cancer cells. The polar periphery of the aminoalcohols benefited from the high boron uptake in CT26 cancer cells with low toxicity, indicating their potential as BNCT agents.
Keywords :
Low cytotoxicity , Water solubility , boron neutron capture therapy , Boron accumulation , o-Carboranylphenol derivatives
