Title of article :
Synthetic studies on amphidinolides C and F: synthesis of the C18–C29 segment of amphidinolide F
Author/Authors :
Armstrong، نويسنده , , Alan and Pyrkotis، نويسنده , , Constantina، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
The C18–C29 segment of amphidinolide F is synthesised in 12 steps from 1,4-butanediol. Key steps include a mono-Sharpless dihydroxylation of a dienoate, iodocyclisation to construct the trans-THF ring and an E-selective Wittig reaction to introduce the C25–C26 olefin.
Keywords :
natural products , Dihydroxylations , iodine , Wittig reactions , cyclisations
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
