Author/Authors :
Beltrلn-Rodil، نويسنده , , Sandra and Donald، نويسنده , , James R. and Edwards، نويسنده , , Michael G. and Raw، نويسنده , , Steven A. and Taylor، نويسنده , , Richard J.K.، نويسنده ,
Abstract :
A number of novel tandem sequences initiated by a retro-aldol process are described along with preliminary scope and limitation studies. These include (i) retro-aldol/Wittig trapping/intramolecular Michael addition, (ii) retro-aldol/aza-Wittig/intramolecular imine addition, (iii) retro-aldol/Henry/intramolecular Michael addition and (iv) retro-aldol/Knoevenagel/intramolecular Michael addition sequences. A range of novel functionalised cyclopentanes, and related systems, are described which should prove to be useful synthetic building blocks.
