Organocatalytic enantioselective domino synthesis of highly functionalized cyclohexanes with an all-carbon quaternary stereocenter
Author/Authors :
Zhao، نويسنده , , Gui-Ling and Dziedzic، نويسنده , , Pawel and Ullah، نويسنده , , Farman and Eriksson، نويسنده , , Lars and Cَrdova، نويسنده , , Armando، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Pages :
5
From page :
3458
To page :
3462
Abstract :
A highly enantioselective organocatalytic domino Michael/aldol reaction is presented. The reaction is catalyzed by chiral amines and gives access to highly functionalized cyclohexanes with one all-carbon quaternary stereocenter and multiple chiral stereocenters in high yields and 83–98% ee.
