• Title of article

    Synthesis of a COMC–estradiol conjugate for targeted, tissue-selective cancer chemotherapy

  • Author/Authors

    James R. and Oaksmith، نويسنده , , Jennifer Marie and Ganem، نويسنده , , Bruce، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    2
  • From page
    3497
  • To page
    3498
  • Abstract
    Guided by a revised mechanism of action for the antitumor agent 2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxy-2-cyclohexenone (COTC) recently advanced by our laboratory, an estradiol conjugate of the bioactive COTC analog, COMC, has been synthesized.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2009
  • Journal title
    Tetrahedron Letters
  • Record number

    1864464