Author/Authors :
Parker، نويسنده , , Gregory D. and Seden، نويسنده , , Peter T. and Willis، نويسنده , , Christine L.، نويسنده ,
Abstract :
Syntheses of 4-acetoxy-2,6-disubstituted tetrahydropyrans via Prins cyclisation of homoallylic alcohols with benzylic aldehydes are described and the methodology is applied in the total synthesis of diarylheptanoid 1 confirming both the structure and absolute configuration of the natural product.