Title of article :
A new short synthesis of 5,6-dimethylxanthenone-4-acetic acid (ASA404, DMXAA)
Author/Authors :
Yang، نويسنده , , Shangjin and Denny، نويسنده , , William A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
A new short synthesis of 5,6-dimethylxanthenone-4-acetic acid (ASA404) is developed. The key steps of the synthesis are dibromination of 3,4-dimethylbenzoic acid, followed by regioselective coupling with 2-hydroxyphenylacetic acid and subsequent cyclodehydration.
Keywords :
ASA404 , DMXAA , Synthesis , Anti-vascular agent
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
