Author/Authors :
Abbas، نويسنده , , Cécile and Pickaert، نويسنده , , Guillaume and Didierjean، نويسنده , , Claude and Grégoire، نويسنده , , Brigitte Jamart and Vanderesse، نويسنده , , Régis، نويسنده ,
Abstract :
The preparation of 2:1-[α/aza]-oligomer precursors is described via Mitsunobu and exchange of protecting groups protocols in four steps in good yields starting from N-tert-butyloxycarbonylaminophtalimide. Conformational studies showed that these building blocks further led to β-turn-like folded 2:1-[α/aza]-trimer which suggests that they are good candidates to form foldamers.
Keywords :
Pseudopeptide , Azapeptide , Mitsunobu , Exchange of protecting group
