Title of article
A simple, efficient, and selective deuteration via a flow chemistry approach
Author/Authors
Andrلs and Mلndity، نويسنده , , Istvلn M. and Martinek، نويسنده , , Tamلs A. and Darvas، نويسنده , , Ferenc and Fülِp، نويسنده , , Ferenc، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
4372
To page
4374
Abstract
A simple and efficient deuteration methodology has been established for a wide variety of substrates using a continuous flow hydrogenation reactor. The described procedure is many times faster (1 mg min−1) compared to literature methods and the purity of the crude product can be as high as 99%. The deuterium source is D2O, the consumption of which is very low.
Keywords
Heterogenous catalysis , Deuteration , Flow chemistry , Reduction , PALLADIUM
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1865114
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