Title of article
Novel enantioselective direct aldol-type reaction promoted by a chiral phosphine oxide as an organocatalyst
Author/Authors
Kotani، نويسنده , , Shunsuke and Shimoda، نويسنده , , Yasushi and Sugiura، نويسنده , , Masaharu and Nakajima، نويسنده , , Makoto، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
4602
To page
4605
Abstract
Chiral phosphine oxide successfully catalyzed the direct aldol-type reactions of cyclohexanone derivatives and benzaldehyde derivatives in high stereoselectivities. The reaction mechanism involves the in situ formation of trichlorosilyl enol ethers. The present reaction could be extended to the cross-aldol reactions between two aldehydes.
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1865289
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