Author/Authors :
Kotani، نويسنده , , Shunsuke and Shimoda، نويسنده , , Yasushi and Sugiura، نويسنده , , Masaharu and Nakajima، نويسنده , , Makoto، نويسنده ,
Abstract :
Chiral phosphine oxide successfully catalyzed the direct aldol-type reactions of cyclohexanone derivatives and benzaldehyde derivatives in high stereoselectivities. The reaction mechanism involves the in situ formation of trichlorosilyl enol ethers. The present reaction could be extended to the cross-aldol reactions between two aldehydes.
