Title of article
Reaction of 2-silylmethylcyclopropyl ketones with in situ oxirane-derived aldehydes and formation of 2-hydroxymethyl tetrahydrofurans
Author/Authors
Yadav، نويسنده , , Veejendra K. and Gupta، نويسنده , , Archana، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
4647
To page
4650
Abstract
The enolates formed from Lewis acid treatment of (2-trimethylsilylmethyl)cyclopropyl alkyl and aryl ketones reacted with aldehydes formed in situ from alkoxy-, aryl- and vinyl-substituted oxiranes to generate aldol products in good yields. Selected aldol products were conveniently transformed into highly substituted tetrahydrofurans under oxidative conditions.
Keywords
Oxirane , (2-Trimethylsilylmethyl)cyclopropyl ketone , aldol , Oxidative ring closure , 2-Hydroxymethyl tetrahydrofuran
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1865323
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