Author/Authors :
Wang، نويسنده , , Guo-Cai and Wang، نويسنده , , Ying and Williams، نويسنده , , Ian D. and Sung، نويسنده , , Herman Ho-Yung and Zhang، نويسنده , , Xiao-Qi and Zhang، نويسنده , , Dong-Mei and Jiang، نويسنده , , Ren-Wang and Yao، نويسنده , , Xin-Sheng and Ye، نويسنده , , Wen-Cai، نويسنده ,
Abstract :
Andrographolactone (1), possessing an unprecedented diterpene skeleton, was isolated from the EtOAc extract of the aerial parts of Andrographis paniculata. Its structure was established by NMR, IR, UV, and HRESIMS data and subsequently confirmed by X-ray diffraction analysis. A possible biogenetic pathway of 1 was also proposed. Bioassay showed that 1 exhibited cytotoxic activity.
Keywords :
Acanthaceae , Andrographis paniculata , Diterpene , Andrographolactone
