Author/Authors :
Ismail ، نويسنده , , Intan Safinar and Nagakura، نويسنده , , Yuta and Hirasawa، نويسنده , , Yusuke and Hosoya، نويسنده , , Takahiro and Lazim، نويسنده , , Mohd Izwan Mohd and Lajis، نويسنده , , Nordin Hj and Morita، نويسنده , , Hiroshi، نويسنده ,
Abstract :
Two novel triterpenes, acutaxylines A (1) and B (2) consisting of a cyclopentenone side chain at C-17 and an oxepan-2-ol, were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was determined by NOESY correlations. Acutaxyline B showed moderate cytotoxicity against human blood premyelocytic leukemia cells.