Title of article :
C–N bond forming reaction under copper catalysis: a new synthesis of 2-substituted 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolines
Author/Authors :
Layek، نويسنده , , Mohosin and Dhanunjaya Rao، نويسنده , , A.V. and Gajare، نويسنده , , Vikas and Kalita، نويسنده , , Dipak and Barange، نويسنده , , Deepak Kumar and Islam، نويسنده , , Aminul and Mukkanti، نويسنده , , K. and Pal، نويسنده , , Manojit، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
We report copper-catalyzed intramolecular cyclization of 8-alkynyl-1,2,3,4-tetrahydroquinolines, obtained via a Pd/C-mediated Sonogashira coupling in water, to afford 2-substituted 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolines. Further functionalization of the compounds synthesized was carried out under Heck, Sonogashira, and Suzuki reaction conditions.
Keywords :
2 , 1-ij]quinoline , C–N bond , Copper , C–C bond , PALLADIUM
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
