Title of article :
Methyl 2-methoxytetrafluoropropionate as a synthetic equivalent of methyl trifluoropyruvate in the Claisen condensation. The first synthesis of 2-(trifluoroacetyl)chromones and 5-aryl-2-hydroxy-2-(trifluoromethyl)furan-3(2H)-ones
Author/Authors :
Irgashev، نويسنده , , Roman A. and Sosnovskikh، نويسنده , , Vyacheslav Ya. and Kalinovich، نويسنده , , Nataliya and Kazakova، نويسنده , , Olesya and Rِschenthaler، نويسنده , , Gerd-Volker، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
2-(Trifluoroacetyl)chromones and 5-aryl-2-hydroxy-2-(trifluoromethyl)furan-3(2H)-ones were obtained in good yields via the Claisen condensation of acetophenones with methyl 2-methoxytetrafluoropropionate, followed by sulfuric acid-mediated deprotection of the reaction products.
Keywords :
Deprotection , Trifluoromethyl 1 , 4-triketones , 2 , Methyl 2-methoxytetrafluoropropionate , Acetophenones , Claisen condensation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
