Author/Authors :
Harada، نويسنده , , Tadao and Kubota، نويسنده , , Yuki and Kamitanaka، نويسنده , , Takashi and Nakamura، نويسنده , , Kaoru and Matsuda، نويسنده , , Tomoko، نويسنده ,
Abstract :
A novel method to enable asymmetric reduction of ketones by an alcohol dehydrogenase from Geotrichum candidum in a supercritical carbon dioxide and water biphasic system is described. The addition of sodium bicarbonate improved the reactivity up to a practical level while retaining excellent enantioselectivity.
