• Title of article

    Synthesis of highly functionalized oxazines by Vilsmeier cyclization of amidoalkyl naphthols

  • Author/Authors

    Damodiran، نويسنده , , M. and Panneer Selvam، نويسنده , , N. and Perumal، نويسنده , , Paramasivan T. Perumal، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    5
  • From page
    5474
  • To page
    5478
  • Abstract
    The intramolecular cyclization of amidoalkyl naphthols by Vilsmeier reagent produced 1,3-oxazines. The Vilsmeier reagent (chloromethylenedimethylammonium chloride) has been used as an efficient and cheap acid activator for the one-step synthesis of oxazine derivatives. A mechanism involving sequential haloformylation and intramolecular nucleophilic cyclization is proposed.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2009
  • Journal title
    Tetrahedron Letters
  • Record number

    1865920