Author/Authors :
Damodiran، نويسنده , , M. and Panneer Selvam، نويسنده , , N. and Perumal، نويسنده , , Paramasivan T. Perumal، نويسنده ,
Abstract :
The intramolecular cyclization of amidoalkyl naphthols by Vilsmeier reagent produced 1,3-oxazines. The Vilsmeier reagent (chloromethylenedimethylammonium chloride) has been used as an efficient and cheap acid activator for the one-step synthesis of oxazine derivatives. A mechanism involving sequential haloformylation and intramolecular nucleophilic cyclization is proposed.
