Title of article
An expedient synthesis of poly-substituted pyrroles from γ-ketonitriles via indium-mediated Barbier reaction strategy
Author/Authors
Kim، نويسنده , , Sung-Hwan and Kim، نويسنده , , Se-Hee and Lee، نويسنده , , Ka Young and Kim، نويسنده , , Jae Nyoung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
5744
To page
5747
Abstract
We developed an efficient synthetic strategy of poly-substituted pyrroles via an indium-mediated Barbier type allylation from γ-ketonitriles. Initial attack of allylindium species occurred at the nitrile group selectively to form the enamine intermediate, which reacted with the ketone group intramolecularly to furnish the pyrroles.
Keywords
Barbier reaction , Indium , pyrroles , ?-Ketonitriles
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866108
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