Author/Authors :
Das، نويسنده , , Bhaskar C. and Mahalingam، نويسنده , , Sakkarapalayam M. and Mohapatra، نويسنده , , Pranoy، نويسنده ,
Abstract :
Guanidine-containing new retinoids 1–4 were synthesized through the addition of guanidine to the activated carboxylic acids (retinoids) promoted by carbonyldiimidazole (CDI). A set of structurally and functionally diverse guanidine derivatives of retinoids were obtained in high yields (78–82%). We are in the process of studying the biological effect of these molecules on retinoic acid signaling pathways.
