Title of article
Cu(OTf)2/Cu-catalyzed four-component reaction: a facile synthesis of α-alkoxytriazoles via click chemistry
Author/Authors
Yadav، نويسنده , , J.S and Subba Reddy، نويسنده , , B.V. and Madhusudhan Reddy، نويسنده , , G. and Rehana Anjum، نويسنده , , S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
3
From page
6029
To page
6031
Abstract
Aldehyde, alcohol, azide, and alkyne undergo smooth coupling by means of acetal formation, azidation, and a subsequent ‘click reaction’ in the presence of copper(II) triflate and copper metal in acetonitrile to furnish α-alkoxy-1,2,3-triazoles in good yields. The method provides a convenient route to prepare a wide range of triazoles in a one-pot operation via a four-component reaction.
Keywords
Click reactions , Hemi-acetal formation , Azidation , ?-Alkoxytriazoles
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866310
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