Author/Authors :
Ito، نويسنده , , Fumihiro and Nakamura، نويسنده , , Tomoko and Yorita، نويسنده , , Satoko and Danjo، نويسنده , , Hiroshi and Yamaguchi، نويسنده , , Kentaro، نويسنده ,
Abstract :
A new ionization method that uses metal-complex-based ionization probes containing the 2,6-bis(oxazolinyl)pyridine (pybox) ligand is presented. This method was proven to effectively ionize large complex molecules, including biomolecules. The preparation of the charged probes and their application to the ionization of biomolecules using cold-spray ionization mass spectrometry are shown.