Title of article
Regioselective synthesis of poly-substituted thiophenes from Baylis–Hillman adducts
Author/Authors
Lee، نويسنده , , Hyun Seung and Kim، نويسنده , , Se-Hee and Kim، نويسنده , , Jae Nyoung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
6480
To page
6483
Abstract
The reaction of Baylis–Hillman acetates and ethyl mercaptoacetate in the presence of DBU in DMF produced 2,3,4-trisubstituted tetrahydrothiophenes at room temperature as a diastereomeric mixture via the sequential SN2′ and Michael addition. Aromatization of tetrahydrothiophenes by DDQ oxidation produced 2,3,4-trisubstituted thiophenes in good yields.
Keywords
Thiophenes , Baylis-Hillman adducts , Tetrahydrothiophenes , DDQ
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1866623
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