Author/Authors :
Ward، نويسنده , , Timothy R. and Turunen، نويسنده , , Brandon J. and Haack، نويسنده , , Torsten and Neuenswander، نويسنده , , Benjamin and Shadrick، نويسنده , , William and Georg، نويسنده , , Gunda I. Georg، نويسنده ,
Abstract :
A library of 72 quinolones was synthesized from substituted anthranilic acids, using ynone intermediates. These masked β-dicarbonyl synthons allowed cyclization under milder conditions than previously reported quinolone syntheses.
