Author/Authors :
Castellano، نويسنده , , Sabrina and Santoriello، نويسنده , , Marisabella and Campiglia، نويسنده , , Pietro and Cardillo، نويسنده , , Giovanna and Bertamino، نويسنده , , Alessia and Gomez-Monterrey، نويسنده , , Isabel and Novellino، نويسنده , , Ettore and Sbardella، نويسنده , , Gianluca، نويسنده ,
Abstract :
An inexpensive and regioselective approach to dihydrothieno[3,2-g]quinoline-4,9-dione is reported. A combination of a mild version of Skraup reaction with a sequential substitution/Michael addition allowed the selective preparation in acceptable yield of a pharmacologically important quinone derivative, previously obtained only in trace and together with the other regioisomer.
