Title of article
Novel ninhydrin adduct of catechin with potent antioxidative activity
Author/Authors
Fukuhara، نويسنده , , Kiyoshi and Ohno، نويسنده , , Akiko and Nakanishi، نويسنده , , Ikuo and Imai، نويسنده , , Kohei and Nakamura، نويسنده , , Asao and Anzai، نويسنده , , Kazunori and Miyata، نويسنده , , Naoki and Okuda، نويسنده , , Haruhiro، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
4
From page
6989
To page
6992
Abstract
The reaction of ninhydrin with (+)-catechin in the presence of TMSOTf resulted in condensation product 1, which consists of a 2:1 mixture of epimers at the C-2 position. The antioxidative radical-scavenging activity of 1 against the galvinoxyl radical, acting as an oxyl radical, was significantly enhanced compared to (+)-catechin. Our results offer a new method for chemical modification of a natural phenolic antioxidant.
Keywords
Ninhydrin , Galvinoxyl radical , Radical scavenging , Catechin , antioxidant
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1867002
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