Title of article
Copper(II) bromide as an efficient catalyst for the selective protection and deprotection of alcohols as bis(4-methoxyphenyl)methyl ethers
Author/Authors
Mezaache، نويسنده , , Rofia and Dembelé، نويسنده , , Yénimégué Albert and Bikard، نويسنده , , Yann and Weibel، نويسنده , , Jean-Marc and Blanc، نويسنده , , Aurélien and Pale، نويسنده , , Patrick، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2009
Pages
5
From page
7322
To page
7326
Abstract
In a cheap and eco-friendly process, primary and secondary alcohols were easily protected as bis(methoxyphenyl)methyl (BMPM) ethers in good yields using CuBr2 as a catalyst in acetonitrile at room temperature. Deprotection could easily be achieved using the same catalyst but in ethanol. Both Cu-catalyzed protection and deprotection were orthogonal to other methods and fully compatible with other functional groups.
Keywords
alcohols , Copper , Protecting group , Arylmethyl , Bis(methoxyphenyl)methyl
Journal title
Tetrahedron Letters
Serial Year
2009
Journal title
Tetrahedron Letters
Record number
1867251
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