Title of article
Fast production of highly concentrated reactive [18F] fluoride for aliphatic and aromatic nucleophilic radiolabelling
Author/Authors
Aerts، نويسنده , , Joël and Voccia، نويسنده , , Samuel and Lemaire، نويسنده , , Christian and Giacomelli، نويسنده , , Fabrice and Goblet، نويسنده , , David and Thonon، نويسنده , , David and Plenevaux، نويسنده , , Alain and Warnock، نويسنده , , Geoffrey and Luxen، نويسنده , , André، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
64
To page
66
Abstract
The use of a polymeric solid support loaded with a long alkyl chain quaternary ammonium allows the rapid and efficient recovery of cyclotron produced [18F]F− from [18O]water to a low water content organic solution compatible with fast nucleophilic labelling of most precursors for PET radiopharmaceuticals in high yield.
Keywords
Radiofluorination , Radiopharmaceuticals , fluoride , nucleophilic substitution , Positron emission tomography , SPE , F-18
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1870463
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