Author/Authors :
Han، نويسنده , , Ying and Ebinger، نويسنده , , Katalin and Vandevier، نويسنده , , Lauren E. and Maloney، نويسنده , , Jennifer W. and Nirschl، نويسنده , , David S. and Weller، نويسنده , , Harold N.، نويسنده ,
Abstract :
A new, divergent, efficient, and selective synthesis of furo- and thieno[2,3-d]pyrimidin-4-amine derivatives by microwave irradiation has been developed starting from readily available amines and substituted 2-aminofuran-3-carbonitrile or 2-aminothiophene-3-carbonitrile, which are converted into corresponding formamidines in DMF using benzenesulfonyl chloride.