Author/Authors :
Voskressensky، نويسنده , , Leonid G. and Listratova، نويسنده , , Anna V. and Bolshov، نويسنده , , Alexander V. and Bizhko، نويسنده , , Oksana V. and Borisova، نويسنده , , Tatiana N. and Varlamov، نويسنده , , Alexey V.، نويسنده ,
Abstract :
Reaction of 5-bromo-2-methyl-8-nitro-1,2,3,4-tetrahydroisoquinoline with activated alkynes affords stable tetrahydropyrrolo[2,1-a]isoquinolin-4-ium ylides. Further reactions of ylide 2 gives access to substituted dihydropyrrolo[2,1-a]isoquinolines in good yields.