Title of article :
Synthesis and reactions of 3-halomethyl-substituted oxazine N-oxides
Author/Authors :
Mikhaylov، نويسنده , , Andrey A. and Dilman، نويسنده , , Alexander D. and Kunetsky، نويسنده , , Roman A. and Khomutova، نويسنده , , Yulia A. and Struchkova، نويسنده , , Marina I. and Korlyukov، نويسنده , , Alexander A. and Ioffe، نويسنده , , Sema L. and Tartakovsky، نويسنده , , Vladimir A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
A series of 3-halomethyl-5,6-dihydro-1,2-oxazine N-oxides (halogen = Cl, Br, I) is prepared from 4-phenyl-3,6,6-trimethyl-5,6-dihydro-4H-oxazine N-oxide by means of a silylation/halogenation sequence. The obtained halogenated N-oxides undergo reactions typical of cyclic six-membered nitronates including 1,3-dipolar cycloaddition, addition of nucleophiles, and substitution of the halogen by C-, S-, and N-nucleophiles.
Keywords :
Halogenation , Nitronates , 5 , 6-Dihydro-1 , 2-Oxazine-N-oxides
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
