Title of article :
Highly stereocontrolled synthesis of fluorinated 2,6-trans dihydropyrans via Prins cyclization
Author/Authors :
Luo، نويسنده , , Hai-Qing and Hu، نويسنده , , Xu-Hong and Loh، نويسنده , , Teck-Peng، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
A highly efficient method for the synthesis of fluorinated 2,6-trans dihydropyrans via BF3·Et2O-promoted Prins cyclization of allenic alcohols and aldehydes is developed. Various 2,6-trans fluorodihydropyrans are obtained in moderate to good yields with excellent diastereoselectivities.
Keywords :
Fluorine chemistry , Prins cyclization , Allenic alcohols , trans-Dihydropyrans , BF3·Et2O
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
