Title of article
Enantioselective syntheses of candenatenins B and C using a chiral anthracene auxiliary
Author/Authors
Jones، نويسنده , , Amanda L. and Liu، نويسنده , , Xiang and Snyder، نويسنده , , John K.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
1091
To page
1094
Abstract
The asymmetric syntheses of two anticancer natural products, candenatenins B and C, are described, leading to a revision of the originally assigned stereochemistries. The syntheses follow a Diels–Alder/retro-Diels Alder strategy using a chiral anthracene auxiliary to access both targets with 90% ee. The inherent structural qualities of the auxiliary allow for both regio- and diastereoselective transformations.
Keywords
Diels–Alder reaction , Candenatenin , Chiral anthracene , Chiral 4-substituted cyclohexenones , asymmetric synthesis
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871195
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