Title of article
A straightforward synthesis of pyrimido[4,5-b]quinoline derivatives assisted by microwave irradiation
Author/Authors
Quiroga، نويسنده , , Jairo and Trilleras، نويسنده , , Jorge and Insuasty، نويسنده , , Braulio and Abonيa، نويسنده , , Rodrigo and Nogueras، نويسنده , , Manuel and Marchal، نويسنده , , Antonio and Cobo، نويسنده , , Justo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
1107
To page
1109
Abstract
Several pyrimido[4,5-b]quinolines, flavin analogues, have been prepared by assisted microwave intramolecular cyclization of N4-substituted-2,4-diamino-6-chloropyrimidine-5-carbaldehydes. The reaction takes place with hydrolysis of amino-group and chlorine. Particularly valuable features of this method included the broader substrate scope and operational simplicity as well as increased safety for small-scale high-speed synthesis.
Keywords
Deazaflavins , cyclization , Microondas irradiation , 5-b]quinolines
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871210
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