Author/Authors :
Fujikawa، نويسنده , , Kohki and Nohara، نويسنده , , Tomohiro and Imamura، نويسنده , , Akihiro and Ando، نويسنده , , Hiromune and Ishida، نويسنده , , Hideharu and Kiso، نويسنده , , Makoto، نويسنده ,
Abstract :
A cyclic glucosyl ceramide (GlcCer) acceptor has been developed as a versatile building block for the synthesis of complex ganglioside. A macrocyclic GlcCer acceptor, which was the product of intramolecular glycosylation between glucose and ceramide, exhibited high reactivity during the coupling reactions with a variety of complex oligosaccharyl donors, thereby furnishing the corresponding ganglioside frameworks in high yields.
Keywords :
ganglioside , Intramolecular glycosylation , Glucosyl ceramide , Sialic acid
