Title of article :
Analysis of kinamycin D-mediated DNA cleavage
Author/Authors :
Heinecke، نويسنده , , Christine L. and Melander، نويسنده , , Christian، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Pages :
4
From page :
1455
To page :
1458
Abstract :
Kinamycin D is a potent antitumor antibiotic; however the biological mode of action is poorly understood. Recent efforts suggest the natural product is capable of generating reactive oxygen species under acidic pH to induce DNA damage in the presence of a reducing agent.
Journal title :
Tetrahedron Letters
Serial Year :
2010
Journal title :
Tetrahedron Letters
Record number :
1871442
Link To Document :
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